Severe Calciphylaxis in A Patient with End Stage Renal Disease

A case of severe calciphylaxis in a patient with End Stage Renal Disease on peritoneal dialysis is presented. Diagnosis was based on medical history and clinical findings and was confirmed by skin biopsy. A multidisciplinary medical team was involved in the patient’s management who was treated with intravenous sodium thiosulfate, intensified hemodialysis sessions, parathyroidectomy and surgical debridement. Calciphylaxis is a rare manifestation of chronic kidney disease, although non uremic causes have also been identified. The prognosis is generally poor. When confronting the disease, the physician does not stand on solid ground due to the lack of well designed treatment studies.